Notch-Jagged1 signaling and response to bevacizumab therapy in advanced colorectal cancer: A glance to radiomics or back to physiopathology?

Francesca Negri,Lorena Bottarelli,Giuseppe Pedrazzi, Michele Maddalo,Ludovica Leo,Gianluca Milanese,Roberto Sala, Michele Lecchini,Nicoletta Campanini,Cecilia Bozzetti, Andrea Zavani, Gianluca Di Rienzo,Cinzia Azzoni,Enrico Maria Silini,Nicola Sverzellati,Federica Gaiani,Gian Luigi De' Angelis,Letizia Gnetti

Frontiers in Oncology（2023）

引用 0|浏览5

暂无评分

摘要

These results show that high NICD and Jag1 expression are associated with progressive disease and early disease progression to anti VEGF-based therapy; the preliminary radiomic analyses show that the integration of quantitative information with clinical and histological data display the highest performance in predicting the outcome of CRC patients.

查看译文

关键词

Jagged-1,Notch signaling pathway,bevacizumab,colorectal cancer,therapy resistance

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要