Biocompatibility of Subperiosteal Dental Implants: Effects of Differently Treated Titanium Surfaces on the Expression of ECM-Related Genes in Gingival Fibroblasts.
Journal of functional biomaterials(2023)
摘要
Our observations suggest that the titanium alloys used for manufacturing subperiosteal dental implants do not produce cytotoxic or proinflammatory effects on gingival fibroblasts, and that sandblasting acid-etching may be the surface treatment of choice as to stimulate the differentiation of gingival fibroblasts in the direction of attachment and migration, i.e., the features allegedly associated with a more efficient implant osteointegration, wound healing, and connective tissue seal formation.
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关键词
collagen type I-alpha chain 1,fibronectin,focal adhesion kinase,gene expression,gingival fibroblasts,subperiosteal implants,titanium alloys,vinculin,wound healing
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