CD8+ T Cells and PD-L1 Expression as Prognostic Indicators in a Low Prevalence of HPV-Associated Oropharyngeal Squamous Cell Carcinoma.

Kawita Atipas,Natthawadee Laokulrath,Janjira Petsuksiri,Narin Ratanaprasert,Warut Pongsapich

Current oncology (Toronto, Ont.)（2023）

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摘要

The positivity of p16 and the density of CD8+ TIL were associated with better OS in OPSCC, while the status of PD-L1 was not significantly related to OS. OPSCC with type I TME (PD-L1+/TIL+) showed the best prognosis of all types of TME.

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关键词

CD8,PD-L1,human papillomavirus (HPV),oropharyngeal squamous cell carcinoma (OPSCC),p16,survival

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