Lack of evidence that fibrillin1 regulates bone morphogenetic protein 4 activity in kidney or lung.

Autumn McKnite,Hyung-Seok Kim,Joshua Silva,Jan L Christian

Developmental dynamics : an official publication of the American Association of Anatomists（2023）

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摘要

These findings do not support the hypothesis that FBN1 plays a role in promoting BMP4 ligand stability or signaling, nor do they support the alternative hypothesis that FBN1 sequesters BMP4 in a latent form, as is the case for other BMP family members.

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关键词

BMP4,fibrillin1,kidney,lung,mouse

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