Five-year cardiovascular outcomes in patients with chronic myeloid leukemia treated with imatinib, dasatinib, or nilotinib: A cohort study using data from a large multinational collaborative network.

Frontiers in cardiovascular medicine(2023)

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摘要
In this retrospective study with a large number of patients with CML, those treated with nilotinib had a higher 5-year ratio of ACE, while patients with dasatinib showed a lower ratio than patients with imatinib. The ratio of heart failure was higher in patients with imatinib than in patients with dasatinib, but not when compared to nilotinib.
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关键词
breakpoint cluster region-abelson (BCR-ABL),cardio-onco-hematology,cardiovascular safety,chronic myeloid leukemia,tyrosine kinase inhibitor (TKI)
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