Characterization of the Stereoselective Disposition of Bupropion and Its Metabolites in Rat Plasma and Brain.
European journal of drug metabolism and pharmacokinetics(2023)
摘要
The temporal shift in K among the different molecular forms provides evidence regarding the operation of carrier-mediated transport and/or within-brain metabolism of bupropion, and, thereby, fresh insight regarding the causes of intersubject variability in the safety and efficacy of bupropion therapy.
更多查看译文
关键词
bupropion,rat plasma,metabolites,stereoselective disposition
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要