Stress-related reduction of hippocampal subfield volumes in major depressive disorder: A 7-Tesla study.

Judy Alper,Rui Feng,Gaurav Verma,Sarah Rutter,Kuang-Han Huang,Long Xie,Paul Yushkevich,Yael Jacob,Stephanie Brown,Marin Kautz,Molly Schneider,Hung-Mo Lin,Lazar Fleysher,Bradley N Delman,Patrick R Hof,James W Murrough,Priti Balchandani

Frontiers in psychiatry（2023）

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摘要

Determining biomarkers for MDD and TRD pathophysiology through segmentation on high-resolution MRI data and understanding the effects of stress on these regions can enable better assessment of biological response to treatment selection and may elucidate the underlying mechanisms of depression.

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关键词

depression,hippocampus,magnetic resonance imaging,stress,subfields,ultrahigh field MRI

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