Fe-Catalyzed Alkylazidation of alpha-Trifluoromethylalkenes: An Access to Quaternary Stereocenters Containing CF3 and N3 Groups

A concise Fe-catalyzed alkylazidation of alpha-trifluor-omethylalkenes via a C-C bond cleavage/radical addition/ azidation cascade is described. This protocol features a broad substrate scope, excellent functional group compatibility, and the ability to be performed on a gram scale, thus offering a practical and step-economic approach to the synthetically useful tertiary alpha- trifluoromethyl azides.