The Therapeutic Mechanism of Schisandrol A and Its Metabolites on Pulmonary Fibrosis Based on Plasma Metabonomics and Network Analysis.

Xijier Qiaolongbatu,Wenjuan Zhao,Xucong Huang,Feng Qian,Xinyi Yang,Jiaqi Wu,Cui Ma,Han Qu,Li Wang,Guorong Fan,Zhenghua Wu

Drug design, development and therapy（2023）

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摘要

The results suggested the feasibility of combining metabolomics and network analysis to reflect the effects of Sch A on the biological network and the metabolic state of PF and to evaluate the drug efficacy of Sch A and its related mechanisms.

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关键词

mechanism of action,metabonomics,network analysis,pulmonary fibrosis,schisandrol A

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