Osteoblasts-Derived Exosomal lncRNA-MALAT1 Promotes Osteoclastogenesis by Targeting the miR-124/NFATc1 Signaling Axis in Bone Marrow-Derived Macrophages.

Chenyi Zhang,Lai Pan,Haizheng Zhang,Ting Ke,Yuxuan Yang, Lan Zhang,Lili Chen,Jingyi Tan

International journal of nanomedicine（2023）

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摘要

LncRNA MALAT1 functioned as an endogenous sponge by competing for miR-124 binding to regulate NFATc1 expression, accelerating the progression of osteoclastogenesis.

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关键词

exosome,lncRNA,miRNA-124,osteoclast differentiation

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