The impact of impaired tissue fixation in resected non-small-cell lung cancer on protein deterioration and DNA degradation.

Rogier Butter,Hans Halfwerk,Teodora Radonic,Birgit Lissenberg-Witte,Erik Thunnissen

Lung cancer (Amsterdam, Netherlands)（2023）

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摘要

Impaired tissue fixation of resected lung tumors results in decreased IHC staining intensity in some parts of the tumor. This may impact the reliability of IHC analysis.

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关键词

DNA degradation,Immunohistochemistry,Non-small cell lung cancer,Pre-analytic tissue handling,Surgical pathology,Tissue fixation

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