The Interaction Effect of 27-Hydroxycholesterol Metabolism Disorder and CYP27A1 Single Nucleotide Polymorphisms in Mild Cognitive Impairment: Evidence from a Case-Control Study.

Molecular nutrition & food research(2023)

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摘要
The results show that 27-OHC metabolic disorder is associated with MCI and multi-domain cognitive function. CYP27A1 SNPs is correlated to cognitive function, while the interaction between 27-OHC and CYP27A1 SNPs need further study.
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关键词
27-hydroxycholesterol,Apolipoprotein E,CYP27A1,mild cognitive impairment,single nucleotide polymorphisms
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