Hypertension as a Novel Link for Shared Heritability in Age at Menarche and Cardiometabolic Traits.
The Journal of clinical endocrinology and metabolism（2023）
摘要
Our study highlights the usefulness of cross-trait analyses for identifying shared etiology between age at menarche and cardiometabolic traits, especially early onset hypertension. The menarche-related loci may contribute to early onset hypertension through endocrinological pathways.
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关键词
age at menarche,cardiometabolic diseases,molecular pathways,shared genes
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