Association of rare, recurrent nonsynonymous variants in the germline of prostate cancer patients of African ancestry.

Jun Wei,Jennifer Beebe-Dimmer,Zhuqing Shi,Christopher Sample,Guifang Yan,Andrew S Rifkin,Azita Sadeghpour,Marta Gielzak,Sodam Choi,David Moon,S Lilly Zheng,Brian T Helfand,Patrick C Walsh,Jianfeng Xu,Kathleen A Cooney,William B Isaacs

The Prostate（2023）

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摘要

This WES study identified two rare, recurrent nonsynonymous PCa risk-associated variants in AA. Confirmation in additional large populations of AA PCa cases and controls is required.

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关键词

African ancestry (AA),germline,nonsynonymous mutation,prostate cancer,whole exome sequencing (WES)

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