Physical Activity and Insulin Sensitivity Independently Attenuate the Effect of FTO rs9939609 on Obesity.

Mette K Andersen,Lars Ängquist,Jette Bork-Jensen,Anna E Jonsson,Sara E Stinson,Camilla H Sandholt,Malte Thodberg,Laura Maarit Pikkupeura,Emily L Ongstad,Niels Grarup,Arne Astrup,Oluf Pedersen,Kristine Williams,Romain Barrès,Thorkild I A Sørensen,Allan Linneberg, Joseph Grimsby,Christopher J Rhodes,Torben Hansen

Diabetes care（2023）

引用 0|浏览32

暂无评分

摘要

Greater PA and IS independently reduced the effect of rs9939609 on obesity. These effects might be mediated through altered expression of FTO in skeletal muscle. Our results indicated that PA and/or other means of increasing insulin sensitivity could counteract FTO-related genetic predisposition to obesity.

查看译文

关键词

insulin sensitivity,obesity,physical activity

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要