A metagenomic study identifies a Prevotella copri enriched microbial profile associated with non-alcoholic steatohepatitis in subjects with obesity.

Sofía Moran-Ramos,Daniel Cerqueda-García,Blanca López-Contreras,Elena Larrieta-Carrasco,Hugo Villamil-Ramírez, Selene Molina-Cruz,Nimbe Torres,Mónica Sánchez-Tapia,Rogelio Hernández-Pando,Carlos Aguilar-Salinas,Teresa Villarreal-Molina,Samuel Canizales-Quinteros

Journal of gastroenterology and hepatology（2023）

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摘要

Our findings suggest that a Prevotella copri dominant bacterial community is associated with a greater risk for NAFLD disease progression, probably linked to higher intestinal permeability and lower capacity for butyrate production.

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关键词

NAFLD,Prevotella,gut microbiome,lipopolysaccharides

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