Patterns of mutations in nine cancer-related genes and PAF development among smoking male patients diagnosed with bladder cancer.

Eman Alshehri,Amal M Al-Dogmi,Tahani Mohamed Ibrahim Al-Hazani,Maha Abdulla Alwaili,Fatmah Ahmed Safhi,Lina Mohammed Alneghery,Areej Saud Jalal,Ibtesam Sanad Alanazi,Fatima Abdullah AlQassim,Mashael Alhumaidi Alotaibi,Wedad Saeed Al-Qahtani

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine（2023）

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摘要

Smoking of cigarettes provokes PAF development due to urothelial inflammation and rise of mutations in 9 cancer-related genes. These are indicative factors of inducing BC.

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关键词

9 cancer-associated genes,Cigarette smoking,bladder cancer patients,platelet-activating factor (PAF),somatic mutations

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