Does initial skeletal muscle size or sex affect the magnitude of muscle loss in response to 14 days immobilization?
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM(2023)
摘要
We aimed to determine whether there was a relationship between pre-immobilization skeletal muscle size and the mag-nitude of muscle atrophy following 14 days of unilateral lower limb immobilization. Our findings (n = 30) show that pre -immobilization leg fat-free mass and quadriceps cross-sectional area (CSA) were unrelated to the magnitude of muscle atrophy. However, sex-based differences may be present, but confirmatory work is required. In women, pre-immobilization leg fat-free mass and CSA were associated with changes in quadriceps CSA after immobilization (n = 9, r2 = 0.54-0.68; P < 0.05). The extent of muscle atrophy is not affected by initial muscle mass, but there is potential for sex-based differences.
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关键词
atrophy,fat-free mass,cross sectional area
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