A robust computational framework for simulating the dynamics of large assemblies of highly-flexible fibers immersed in viscous flow

The dynamic response of flexible filaments immersed in viscous fluids is important in cell mechanics, as well as other biological and industrial processes. In this paper, we propose a parallel computational framework to simulate the fluid-structure interactions in large assemblies of highly-flexible filaments immersed in a viscous fluid. We model the deformation of each filament in 3D with a C1 geometrically-exact large-deformation finite-element beam formulation and we describe the hydrodynamic interactions by a boundary element discretization of the Stokeslet model. We incorporate a contact algorithm that prevents fiber interpenetration and avoids previously reported numerical instabilities in the flow, thus providing the ability to describe the complex evolution of large clouds of fibers over long time spans. In order to support the required long-term integration, we use implicit integration of the solid-fluid-contact coupling. We address the challenges associated with the solution of the large and dense linear system for the hydrodynamic interactions by taking advantage of the massive parallelization offered by Graphic Processing Units (GPUs), which we test up to 1000 fibers and 45000 degrees of freedom.