Longitudinal assessment of HCV core antigen kinetics to monitor therapeutic response in the age of DAAs.

Suresh Ponnuvel, Arul Prakash,Runal John Steve,George Priya Doss,Ashish Goel,Uday George Zachariah,Chundamannil Eapen Eapen,Grace Rebekah,Rajesh Kannangai,Gnanadurai John Fletcher,Priya Abraham

PloS one（2023）

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摘要

It is the first longitudinal study from India shows that the response rate and kinetics of HCVcAg are comparable to HCV RNA for an extended duration, except at RVR, irrespective of the HCV genotypes, treatment regimen, and liver disease severity. Hence, HCVcAg can be considered as a pragmatic marker to monitor therapeutic response and predict relapse in the era of DAAs.

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hcv core,antigen

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