Analysis of RAS gene mutations in adverse events during first induction chemotherapy in childhood acute lymphoblastic leukemia.

Tianping Chen,Nan Wei,Wenxiu Lv,Lijun Qu,Hongjun Liu

Translational pediatrics（2023）

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摘要

Newly diagnosed ALL in children with mutation is less likely to be associated with fusion gene expression. mutation increases the risk of agranulocytosis duration during first induction chemotherapy, lowers BMI and reduces the risk of hyperbilirubinemia in ALL children.

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关键词

RAS gene mutations,acute lymphoblastic leukemia (ALL),adverse events,first induction chemotherapy

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