Factor V Leiden but not the factor II 20210G>A mutation is a risk factor for premature coronary artery disease: a case-control study in Iran.

Pasquale Agosti,Ilaria Mancini,Saeed Sadeghian,Maria Teresa Pagliari,Seyed Hesameddin Abbasi,Hamidreza Pourhosseini,Mohammadali Boroumand,Masoumeh Lotfi-Tokaldany,Emanuela Pappalardo,Alberto Maino,Frits R Rosendaal,Flora Peyvandi

Research and practice in thrombosis and haemostasis（2023）

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摘要

FVL but not FII rs1799963 was associated with an increased risk of CAD in young Iranians. This risk increased considerably when combined with metabolic cardiovascular risk factors.

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关键词

coronary artery disease,factor II,factor V Leiden,hypercoagulability,myocardial infarction

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