circPKD2 inhibits the glioma cell proliferation, invasion and glycolytic metabolism through regulating the miR-1278/LATS2 axis

Feng Liu,Hao Wu,Guangyong Wu,Jun Long,Jin Dai,Zhifei Wang

Neuroscience Letters（2023）

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摘要

•circPKD2 expression is downregulated in glioma.•circPKD2 can target miR-1278 to regulate LATS2 expression.•circPKD2 inhibits the cell proliferation, invasion, and glycolytic metabolism in glioma by regulating the miR-1278/LATS2 axis.•circPKD2 can function as a tumor suppressor in glioma.

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关键词

circPKD2,miR-1278,LATS2,Glioma,Glycolytic metabolism

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