The first taxonomic and functional characterization of human CAVD-associated microbiota.

Lavinia Curini,Brunilda Alushi,Mary Roxana Christopher,Simone Baldi,Leandro Di Gloria,Pierluigi Stefano, Anna Laganà,Luisa Iannone,Herko Grubitzsch,Ulf Landmesser,Matteo Ramazzotti,Elena Niccolai,Alexander Lauten,Amedeo Amedei

Microbial cell (Graz, Austria)（2023）

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摘要

The presence of microbiota in inflamed CAV samples represents the right trigger point to explain the valve calcification process, encouraging further studies to explore the potential link between bacteria and adaptive immune response and to define the critical role of local microbiota-immunity axis on CAVD development.

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关键词

T cells,aortic valve disease,immune response,microbiota,valve calcification

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