New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany.

Fabian Heinrich, Tobias Huter, Sophie Mertens,Philine Lange, Jessica Vering,Axel Heinemann,Dominik Sebastian Nörz,Armin Hoffmann,Martin Aepfelbacher,Benjamin Ondruschka,Susanne Krasemann,Marc Lütgehetmann

Emerging infectious diseases（2023）

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摘要

We performed autopsies on persons in Germany who died from COVID-19 and observed higher nasopharyngeal SARS-CoV-2 viral loads for variants of concern (VOC) compared with non-VOC lineages. Pulmonary inflammation and damage appeared higher in non-VOC than VOC lineages until adjusted for vaccination status, suggesting COVID-19 vaccination may mitigate pulmonary damage.

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Alpha variant,B.1.1.529,B.1.1.7,B.1.617.2,COVID-19,Delta variant,Germany,Omicron variant,SARS,SARS-CoV-2,VOC,coronavirus,coronavirus disease,organ tropism,pulmonary damage,respiratory infections,severe acute respiratory syndrome coronavirus 2,variants of concern,viral load,viruses,zoonoses

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