Genetically Predicted Differences in Systolic Blood Pressure and Risk of Cardiovascular and Noncardiovascular Diseases: A Mendelian Randomization Study in Chinese Adults.

Robert Clarke,Neil Wright,Robin Walters,Wei Gan,Yu Guo,Iona Y Millwood,Ling Yang,Yiping Chen,Sarah Lewington,Jun Lv,Canqing Yu,Daniel Avery,Kuang Lin,Kang Wang,Richard Peto,Rory Collins, Liming Li,Derrick A Bennett,Sarah Parish,Zhengming Chen

Hypertension (Dallas, Tex. : 1979)（2023）

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摘要

The findings provide support for initiation of blood pressure-lowering treatment at younger ages and below the conventional cut-offs for hypertension to maximize CVD prevention, albeit the absolute risks of CVD are far greater in older people.

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关键词

Mendelian randomization,cardiovascular diseases,noncardiovascular disease,systolic blood pressure

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