Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility.

Henriette H Nerild,Andreas Brønden,Ida M Gether,Pernille H Hellmann,Mille Baekdal,Matthew P Gillum,Jens S Svenningsen,Bolette Hartmann,Naveen Rathor, Hanna Angelene Kudiyanur Muniraju,Jens F Rehfeld,Jens J Holst,Tina Vilsbøll,David P Sonne,Filip K Knop

Diabetes, obesity & metabolism（2023）

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摘要

Compared with placebo, treatment with liraglutide decreased postprandial FGF19 and GLP-2 concentrations and increased postprandial CCK concentrations, which may explain the delayed postprandial gallbladder refilling observed in individuals with obesity treated with liraglutide.

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关键词

GLP-1 analogue,GLP1,clinical trial,incretin physiology,incretin therapy,liraglutide

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