Circ_0115118 regulates endometrial functions through the miR-138-1-3p/WDFY2 axis in patients with PCOS.

Zi Yang,Fenting Liu,Jiali Bai,Zhenhong Ye,Jingwen Yin,Tianliu Peng,Hongying Shan,Yang Yu,Ping Zhou,Rong Li

Biology of reproduction（2023）

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摘要

This study shows that circ_0115118 expression is dysregulated in the endometria of patients with PCOS and adversely affects endometrial function. Our findings reveal that circ_0115118 may be a potential therapeutic target to improve pregnancy outcomes in women with PCOS.

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circular RNA,endometrium,microRNA,polycystic ovary syndrome,stromal cells

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