Lower T cell response against SARS-CoV-2 variants of concern after mRNA vaccine and risk of breakthrough infections in people with HIV.

José L Casado,Pilar Vizcarra, Sara Martín-Colmenarejo, Judith Del Pino, Sandra Gomez-Maldonado,Adrían Martín-Hondarza,Alejandro Vallejo

AIDS (London, England)（2023）

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摘要

A blunted T-cell response against Delta and Omicron variant is observed in PWH who received two doses of mRNA vaccine. This lower immune response is associated with breakthrough SARS-CoV-2 infections.

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关键词

HIV, immune response, infections, omicron, SARS-CoV-2, vaccine

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