Safety and Efficacy Associated with Long-Term Low Dose Glucocorticoids in Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials

Andriko Palmowski,Sabrina Mai Nielsen,Zhivana Boyadzhieva, Abelina Schneider,Anne Pankow,Linda Hartman,Jose Pereira da Silva,John Kirwan,Siegfried Wassenberg,Christian Dejaco,Robin Christensen,Maarten Boers,Frank Buttgereit

ARTHRITIS & RHEUMATOLOGY（2022）

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摘要

There is very low to moderate QoE for no harm with long-term low dose GCs in RA, except for an increased risk of infections in GC users. The benefit-risk ratio might be reasonable for using low-dose long-term GCs considering the moderate to high quality evidence for disease-modifying properties.

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关键词

Rheumatoid arthritis,adverse events,efficacy,glucocorticoids,meta-analysis,safety,systematic review

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