The activation of histone deacetylases 4 prevented endothelial dysfunction: A crucial mechanism of HuangqiGuizhiWuwu Decoction in improving microcirculation dysfunction in diabetes.

Meijiang Chen,Hong Cheng,Xinyi Chen,Jiangyong Gu,Weiwei Su,Gaize Cai, Yue Yan,Chen Wang,Xiaoye Xia,Kaitong Zhang,Meng Zhang,Haiqiang Jiang,Yongjun Chen,Lin Yao

Journal of ethnopharmacology（2023）

引用 3|浏览19

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摘要

These results prove the key role of HDAC4 in diabetes-induced microvascular dysfunction and underlying epigenetic mechanisms for the protective effect of HGWWD in diabetes.

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关键词

Diabetes,Endothelial dysfunction,HDAC4,HuangqiGuizhiWuwu decoction,Microvascular injury

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