Effectiveness and persistence of acitretin, ciclosporin, fumaric acid esters and methotrexate for patients with moderate-to-severe psoriasis: a cohort study from BADBIR.

Oras A Alabas,Kayleigh J Mason,Zenas Z N Yiu,Philip J Hampton,Nick J Reynolds,Caroline M Owen,Anthony Bewley,Philip M Laws,Richard B Warren,Mark Lunt,Catherine H Smith,Christopher E M Grifﬁths

The British journal of dermatology（2023）

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摘要

The real-world effectiveness and persistence of acitretin, ciclosporin, FAEs and methotrexate were generally low. Previous nonbiologic systemic therapies, male sex, comorbidities and alcohol consumption were risk factors associated with treatment ineffectiveness.

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关键词

psoriasis,acitretin,ciclosporin,methotrexate,moderate-to-severe

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