Rationale and design of the colchicine for the prevention of perioperative atrial fibrillation in patients undergoing major noncardiac thoracic surgery (COP-AF) trial.

American heart journal(2023)

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摘要
COP-AF is a large randomized and blinded trial designed to determine whether colchicine reduces the risk of perioperative AF or MINS in patients who have major noncardiac thoracic surgery.
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关键词
Atrial fibrillation,Colchicine,Inflammation,Myocardial injury,Prevention,Thoracic surgery
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