STAT3 regulation of Mtb-specific T cell function in active pulmonary tuberculosis patients

Ruiqi Chen,Meihui Li,Shuang Qin,Hong Lu,Mo Shen,Xiangyang Lin

International Immunopharmacology（2023）

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摘要

•·T cells in pleural effusion have higher levels of STAT3 phosphorylation.•·Multifunctional T cells of APTB patients have higher pSTAT3 levels.•·The STAT3+ pSTAT3- phenotype of Mtb-specific T cells tended to be more anti-apoptotic.

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关键词

Active pulmonary tuberculosis,STAT3,Mtb-specific T cells

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