Effects of a Polypill, Aspirin, and the Combination of Both on Cognitive and Functional Outcomes: A Randomized Clinical Trial.

Jacqueline J Bosch,Martin J O'Donnell,Peggy Gao,Philip Joseph,Prem Pais,Denis Xavier,Antonio Dans,Patricio Lopez Jaramillo,Salim Yusuf

JAMA neurology（2023）

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摘要

In this randomized clinical trial of patients 65 years or older with vascular risk factors, a polypill, with or without aspirin, was not associated with reduced cognitive outcomes but was associated with reduced functional decline.

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