The T H 22-mediated IL-22 deficiency associated with premature ovarian insufficiency.

Wenzhe Zhang,Shiru Xu,Rongrong Zhang,Zhuqing Li,Nianyu Li,Xiruo Zhang,Yueshuang Lu,Yuehong Bian,Ping Yang,Fang Fang,Yingying Qin,Xue Jiao

American journal of reproductive immunology (New York, N.Y. : 1989)（2023）

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摘要

Our study first demonstrated the significant association between T 22-mediated IL-22 deficiency and ovarian insufficiency, which provide new insights into the autoimmune disturbance and opens new avenues for exogenous IL-22 administration as potential intervention of POI.

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关键词

T helper 22 cell,interleukin 22,interleukin 22 receptor subunit alpha 1,ovarian reserve,premature ovarian insufficiency

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