Lidocaine inhibits osteogenic differentiation of human dental pulp stem cells in vitro .

Eun-Jung Kim,Ji-Uk Yoon,Cheul-Hong Kim,Ji-Young Yoon,Joo-Young Kim,Hyang-Sook Kim,Eun-Ji Choi

The Journal of international medical research（2023）

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摘要

Lidocaine inhibits osteogenic differentiation markers in HDPSCs , even at low concentrations, without cytotoxicity. This study suggests that lidocaine may inhibit osteogenic differentiation in HDPSC-mediated regenerative medicine, including pulp regeneration and repair.

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关键词

Dental pulp stem cells,cytotoxicity,differentiation markers,lidocaine,osteogenic differentiation,regenerative medicine

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