The emerging roles of ferroptosis in organ fibrosis and its potential therapeutic effect

•Fibrosis refers to the process of excessive deposition of extracellular matrix ECM proteins and excessive fibrosis underlies the organ dysfunction or failure.•Ferroptosis, as a new form of regulatory cell death, is driven by iron-dependent lipid peroxidation and can be regulated by many factors and mechanisms.•Ferroptosis has been proposed to be related to the development of fibrosis and is the promising target for treating fibrotic disorders.