Discovery of a novel, liver-targeted thyroid hormone receptor-β agonist, CS271011, in the treatment of lipid metabolism disorders.

Suwen Lin,Shengjian Huang,Zhou Deng, Yu Zhang, Lin Huang, Yanyi Wu, Shuyan Lv, Zhiyi Wang,Ning Huang,Lan Wang, Ziqi Chen,Guangyin Yu,Weihua Yin,You Zhou,Zhengyu Fang

Frontiers in endocrinology(2023)

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摘要
CS271011 is a potent and liver-targeted THR-β agonist for treating lipid metabolism disorders.
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关键词
Resmetirom,dyslipidaemia,steatosis,thyroid hormone receptor,triglycerides
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