Identification of gene signatures associated with ulcerative colitis and the association with immune infiltrates in colon cancer.

Zhaoji Pan,Hao Lin,Yanyan Fu,Fanpeng Zeng, Feng Gu,Guoping Niu,Jian Fang,Bing Gu

Frontiers in immunology（2023）

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摘要

Study results show the involvement of hub genes like CCL3, MMP3, and TIMP1 in the pathogenesis of UC. These genes could serve as a novel pharmacological regulator of UC. These could be used as a therapeutic target for treating patients with UC and may serve as biomarkers for immune cell infiltration in colon cancer.

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GEO dataset,UC,biomarkers,colon cancer,immune

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