Cisplatin or Doxorubicin Reduces Cell Viability via the PTPIVA3-JAK2-STAT3 Cascade in Hepatocellular Carcinoma.

Chao-Jen Li,Hung-Wen Tsai,Yi-Li Chen,Chun-I Wang,Yang-Hsiang Lin,Pei-Ming Chu,Hsiang-Cheng Chi,Yi-Ching Huang,Cheng-Yi Chen

Journal of hepatocellular carcinoma（2023）

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摘要

Therefore, emerging evidence provides a deep understanding of the roles of PTP4A3 in HCC cisplatin/doxorubicin chemoresistance, which can be applied to develop early diagnosis strategies and reveal prognostic factors to establish novel targeted therapeutics to specifically treat HCC.

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关键词

IL-6,PTP4A3,chemoresistance,cisplatin,doxorubicin,hepatocellular carcinoma

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