Gamma Knife Radiosurgery Modulates micro-RNA Levels in Patients with Brain Metastasis.

Imran Khan,Kerime Akdur,Sadaf Mahfooz,Elif Burce Elbasan,Ayten Sakarcan,Busra Karacam,Georges Sinclair,Sahabettin Selek,Fahri Akbas,Mustafa Aziz Hatiboglu

Current radiopharmaceuticals（2023）

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摘要

For this specific population with MBT disease, our data suggest that stereotactic radiosurgery may modulate the expression of circulating tumor-suppressor and oncogenic miRNAs, ultimately enhancing key anti-tumoral responses. Further evaluation with larger cohorts is warranted.

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关键词

Brain metastasis,Gamma Knife radiosurgery,Immune response,MiRNA,Serum levels,Stereotactic radiosurgery,Tumor-suppressor miRNAs,oncogenic miRNAs

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