Possible Mpox Protection from Smallpox Vaccine-Generated Antibodies among Older Adults.

Iván Sanz-Muñoz,Laura Sánchez-dePrada,Javier Sánchez-Martínez,Silvia Rojo-Rello,Marta Domínguez-Gil,Cristina Hernán-García,Virginia Fernández-Espinilla,Raúl Ortiz de Lejarazu-Leonardo,Javier Castrodeza-Sanz,José María Eiros

Emerging infectious diseases（2023）

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摘要

Smallpox vaccination may confer cross-protection to mpox. We evaluated vaccinia virus antibodies in 162 persons ≥50 years of age in Spain; 68.5% had detectable antibodies. Highest coverage (78%) was among persons 71-80 years of age. Low antibody levels in 31.5% of this population indicates that addressing their vaccination should be a priority.

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关键词

Spain,antibodies,immunosenescence,monkeypox,mpox,sexually transmitted infections,smallpox,vaccine,vaccinia,viruses,zoonoses

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