Next-Generation Diagnostics for Pathogens

Veterinary Clinics of North America: Food Animal Practice(2023)

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摘要
Next-generation sequencing (NGS) was initially developed to aid sequencing of the human genome. This molecular method is cost effective for sequencing and characterizing genomes, not only those of humans or animals but also those of bacteria and other pathogens. However, rather than sequencing a single organism, a targeted NGS method can be used to specifically amplify pathogens of interest in a clinical sample for detection and characterization by sequencing. Targeted NGS is an ideal method for ruminant syndromic testing due to its ability to detect a variety of pathogens in a sample with a single test.
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关键词
Ruminant molecular diagnostics,Targeted NGS,Next-generation sequencing pathogen detection,NGS infectious diseases
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