Renin-angiotensin system inhibition and In-hospital mortality in acute coronary syndrome patients with advanced renal dysfunction: Findings from CCC-ACS project and a nationwide electronic health record-based cohort in China.

Based on two nationwide cohorts in China in contemporary practice, we demonstrated that ACEI/ARB therapy initiated within 24 hours of admission is associated with a reduction in in-hospital mortality in ACS patients with advanced renal dysfunction. Clinical Trial Registration: CCC-ACS project was registered at URL: https://www.clinicaltrials.gov. (Unique identifier: NCT02306616).