Avascular fat grafts show lower volume retention but higher hypoxia, angiogenesis, adipocyte proliferation, and macrophage infiltration than vascularized adipocutaneous flaps in an in vivo pilot mouse study Fat grafting vs. flap transfer in mice.

Benjamin Thomas,Jan Warszawski,Florian Falkner,Sonja Bleichert,Valentin Haug,Amir K Bigdeli,Matthias Schulte,Sabrina Hl Hoffmann,Boyan K Garvalov,Caroline Schreiber,Masanari Takamiya,Jonathan P Sleeman,Volker J Schmidt,Ulrich Kneser,Bernd J Pichler,Arno Dimmler,Wilko Thiele

Plastic and reconstructive surgery（2023）

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摘要

Vascularized flaps and avascular lipofilling were compared in experimental mice in vivo. This comparative pilot study suggests differences in recipient site volume retention, adipocyte proliferation, angiogenesis, hypoxia, and macrophage recruitment.

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