Environmental Enrichment Protects Against Cognition Deficits Caused by Sepsis-Associated Encephalopathy.

Yi-Fei Tang, Ya-Jing Duan,Rui-Dong Ge,Xi Lu,Bei-Yao Gao,Jing-Wei Guo,Shan Jiang

Journal of integrative neuroscience（2022）

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摘要

The results of the present study indicated that EE exerts a neuroprotective function on cognitive ability in SAE rats. The effect is achieved by increasing antioxidants, and anti-inflammatory and antiapoptotic capacities. EE can effectively rescue SAE-induced cognitive deficits.

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apoptosis,cecal ligation and perforation,cognition deficits,environmental enrichment,inflammatory cytokines,oxidative stress,sepsis-associated encephalopathy

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