Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants.

Pediatric Allergy and ImmunologyVolume 34, Issue 1 e13902 LETTER TO THE EDITOR Ambient prenatal air pollution exposure is associated with low cord blood IL-17a in infants Olga Gorlanova, Olga Gorlanova orcid.org/0000-0002-3153-7404 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorHeide Oller, Heide Oller University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorAndrea Marten, Andrea Marten University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorLoretta Müller, Loretta Müller Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorJessica Laine-Carmelli, Jessica Laine-Carmelli ISPM, University of Bern, Bern, SwitzerlandSearch for more papers by this authorFabienne Decrue, Fabienne Decrue orcid.org/0000-0003-3005-3018 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorYasmin Salem, Yasmin Salem orcid.org/0000-0001-8731-0885 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorDanielle Vienneau, Danielle Vienneau orcid.org/0000-0002-6309-6439 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorKees de Hoogh, Kees de Hoogh orcid.org/0000-0001-5974-2007 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorAmanda Gisler, Amanda Gisler orcid.org/0000-0002-9708-1200 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorJakob Usemann, Jakob Usemann orcid.org/0000-0002-9987-2866 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorInsa Korten, Insa Korten orcid.org/0000-0002-6184-5280 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorSophie Yammine, Sophie Yammine orcid.org/0000-0001-7720-3445 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorUri Nahum, Uri Nahum University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorNoemi Künstle, Noemi Künstle University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorPablo Sinues, Pablo Sinues orcid.org/0000-0001-5602-2880 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Department of Biomedical Engineering, University of Basel, Allschwil, SwitzerlandSearch for more papers by this authorSven Schulzke, Sven Schulzke orcid.org/0000-0002-5475-6239 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorPhilipp Latzin, Philipp Latzin orcid.org/0000-0002-5239-1571 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorOliver Fuchs, Oliver Fuchs orcid.org/0000-0002-7127-5226 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorMartin Röösli, Martin Röösli orcid.org/0000-0002-7475-1531 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorBianca Schaub, Bianca Schaub orcid.org/0000-0003-1652-8873 Department of Pulmonary and Allergy, Dr. von Hauner Children's Hospital, LMU, University of Munich, Munich, GermanySearch for more papers by this authorUrs Frey, Corresponding Author Urs Frey [email protected] orcid.org/0000-0003-3773-2822 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Correspondence Urs Frey, University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland. Email: [email protected]Search for more papers by this authorthe BILD study group, the BILD study group University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this author Olga Gorlanova, Olga Gorlanova orcid.org/0000-0002-3153-7404 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorHeide Oller, Heide Oller University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorAndrea Marten, Andrea Marten University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorLoretta Müller, Loretta Müller Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorJessica Laine-Carmelli, Jessica Laine-Carmelli ISPM, University of Bern, Bern, SwitzerlandSearch for more papers by this authorFabienne Decrue, Fabienne Decrue orcid.org/0000-0003-3005-3018 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorYasmin Salem, Yasmin Salem orcid.org/0000-0001-8731-0885 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorDanielle Vienneau, Danielle Vienneau orcid.org/0000-0002-6309-6439 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorKees de Hoogh, Kees de Hoogh orcid.org/0000-0001-5974-2007 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorAmanda Gisler, Amanda Gisler orcid.org/0000-0002-9708-1200 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorJakob Usemann, Jakob Usemann orcid.org/0000-0002-9987-2866 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorInsa Korten, Insa Korten orcid.org/0000-0002-6184-5280 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorSophie Yammine, Sophie Yammine orcid.org/0000-0001-7720-3445 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorUri Nahum, Uri Nahum University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorNoemi Künstle, Noemi Künstle University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorPablo Sinues, Pablo Sinues orcid.org/0000-0001-5602-2880 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Department of Biomedical Engineering, University of Basel, Allschwil, SwitzerlandSearch for more papers by this authorSven Schulzke, Sven Schulzke orcid.org/0000-0002-5475-6239 University Children's Hospital Basel UKBB, University of Basel, Basel, SwitzerlandSearch for more papers by this authorPhilipp Latzin, Philipp Latzin orcid.org/0000-0002-5239-1571 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorOliver Fuchs, Oliver Fuchs orcid.org/0000-0002-7127-5226 Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this authorMartin Röösli, Martin Röösli orcid.org/0000-0002-7475-1531 Swiss Tropical and Public Health Institute Basel, Basel, Switzerland University of Basel, Basel, SwitzerlandSearch for more papers by this authorBianca Schaub, Bianca Schaub orcid.org/0000-0003-1652-8873 Department of Pulmonary and Allergy, Dr. von Hauner Children's Hospital, LMU, University of Munich, Munich, GermanySearch for more papers by this authorUrs Frey, Corresponding Author Urs Frey [email protected] orcid.org/0000-0003-3773-2822 University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Correspondence Urs Frey, University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland. Email: [email protected]Search for more papers by this authorthe BILD study group, the BILD study group University Children's Hospital Basel UKBB, University of Basel, Basel, Switzerland Paediatric Respiratory Medicine, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandSearch for more papers by this author First published: 02 January 2023 https://doi.org/10.1111/pai.13902 Editor: Jon Genuneit Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1Decrue F, Gorlanova O, Salem Y, et al. Increased impact of air pollution on lung function in preterm versus term infants: the BILD study. Am J Respir Crit Care Med. 2022; 205: 99-107. 2Hehua Z, Qing C, Shanyan G, Qijun W, Yuhong Z. The impact of prenatal exposure to air pollution on childhood wheezing and asthma: a systematic review. Environ Res. 2017; 159: 519-530. 3Rychlik KA, Secrest JR, Lau C, et al. In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. Proc Natl Acad Sci U S A. 2019; 116: 3443-3448. 4Brandt EB, Kovacic MB, Lee GB, et al. Diesel exhaust particle induction of IL-17A contributes to severe asthma. J Allergy Clin Immunol. 2013; 132: 1194-1204. 5García-Serna AM, Martín-Orozco E, Jiménez-Guerrero P, et al. Cytokine profiles in cord blood in relation to prenatal traffic-related air pollution: the NELA cohort. Pediatr Allergy Immunol. 2022; 33:e13732. 6Tohme S, Yazdani HO, Sud V, et al. Computational analysis supports IL-17A as a central driver of neutrophil extracellular trap-mediated injury in liver ischemia reperfusion. J Immunol. 2019; 202: 268-277. 7Kipen HM, Laskin DL. NETs: a new biomarker of traffic-related air pollution exposure: are they ready to catch fish? Eur Respir J. 2020; 55:2000305. 8Eeftens M, Meier R, Schindler C, et al. Development of land use regression models for nitrogen dioxide, ultrafine particles, lung deposited surface area, and four other markers of particulate matter pollution in the Swiss SAPALDIA regions. Environ Health. 2016; 15: 53. 9Fuchs O, Latzin P, Kuehni CE, Frey U. Cohort profile: the Bern infant lung development cohort. Int J Epidemiol. 2012; 41: 366-376. 10Proietti E, Delgado-Eckert E, Vienneau D, et al. Air pollution modelling for birth cohorts: a time-space regression model. Environ Health. 2016; 15: 61. Volume34, Issue1January 2023e13902 ReferencesRelatedInformation