Identification and validation of a prognostic signature of autophagy, apoptosis and pyroptosis-related genes for head and neck squamous cell carcinoma: to imply therapeutic choices of HPV negative patients.

Zhaodi Nan,Yu Dou,Anwei Chen,Ketao Wang,Jintang Sun,Zhen Meng,Markus Neckenig,Dan Ai,Shaohua Liu,Zuoqing Dong,Chao Ma,Yufeng Cheng,Xun Qu

Frontiers in immunology（2022）

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摘要

We established a prognostic signature and emphasized its implements in the therapeutic choices of HPV negative HNSCC patients, the majority and the poor outcome population of HNSCC.

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关键词

apoptosis,autophagy,head and neck squamous cell carcinoma,human papillomavirus,prognosis,pyroptosis,radiotherapy,tumor microenvironment

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