Skin microcirculation dynamics are impaired in patients with rheumatoid arthritis and no cardiovascular comorbidities.

Panagiota Anyfanti,Eleni Gavriilaki,Panagiotis Dolgyras,Barbara Nikolaidou, Antonia Dimitriadou,Antonios Lazaridis,Konstantinos Mastrogiannis,Nikolaos Koletsos,Areti Triantafyllou,Theodoros Dimitroulas,Spyros Aslanidis,Michael Doumas,Stella Douma,Eugenia Gkaliagkousi

Clinical and experimental rheumatology（2023）

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摘要

Patients with RA present impaired microvascular reactivity regardless of CVD risk factors at a preclinical stage preceding CVD. Assessment of skin microvascular dysfunction may reflect a state of generalised vasculopathy, including myocardial microvascular abnormalities, and serve as a non-invasive surrogate indicator of CVD risk in RA.

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